Titmarsh, H.F. et al.
2020
The Veterinary Record

Clinical records of cats were reviewed. For each cat, data including gender, age, breed, serum albumin and creatinine concentrations and appetite scores were extracted. To assess the effects of different types of diseases, cats were divided into groups dependent on the major body system affected; they were subcategorised into urinary, endocrinopathy, cardiology, gastrointestinal, hepatic, respiratory, neurological, orthopaedic, dermatology or haematology disease groups. The relationship between PCV and serum 25(OH)D was assessed in these groups.
Cats with anaemia had significantly lower 25(OH)D concentrations (median 54.8 nmol/l, n=31) than cats with PCV in the reference range (median 109.0 nmol/l, n=130) (p<0.001). Results showed a positive correlation between serum 25(OH)D and PCV in cats with renal disease, respiratory disease and for cats with gastrointestinal. The relationship between PCV and serum 25(OH)D in hepatic disease was not significant
In conclusion, serum 25(OH)D concentrations are negatively associated with anaemia in hospitalised cats, the findings of this study indicate that low vitamin D could have a role in anaemia and that supplementation could prove beneficial for anaemia resolution.